Caenorhabditis elegans Recognizes a Bacterial Quorum-sensing Signal Molecule through the AWCON Neuron
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چکیده
منابع مشابه
Small molecule inhibitors of bacterial quorum sensing and biofilm formation.
Bacteria monitor their local population densities using small molecules (or autoinducers) in a process known as quorum sensing. Here, we report a new and efficient synthetic route to naturally occurring bacterial autoinducers [N-acyl l-homoserine lactones (AHLs)] that is readily amenable to the synthesis of analogues. This route has been applied in the first synthesis of a library of non-native...
متن کامل5D Bacterial quorum sensing
Quorum sensing is a form of system stimulus and response that is correlated to population density. Many species of bacteria use quorum sensing to coordinate various types of behavior including bioluminescence, biofilm formation, virulence, and antibiotic resistance, based on the local density of the bacterial population [10, 7, 9, 24, 40, 36, 42, 27]. In an analogous fashion, some social insect...
متن کاملInformation processing and signal integration in bacterial quorum sensing
Bacteria communicate using secreted chemical signaling molecules called autoinducers in a process known as quorum sensing. The quorum-sensing network of the marine bacterium Vibrio harveyi uses three autoinducers, each known to encode distinct ecological information. Yet how cells integrate and interpret the information contained within these three autoinducer signals remains a mystery. Here, w...
متن کاملHost modification of a bacterial quorum-sensing signal induces a phenotypic switch in bacterial symbionts.
Bacterial communities colonize epithelial surfaces of most animals. Several factors, including the innate immune system, mucus composition, and diet, have been identified as determinants of host-associated bacterial communities. Here we show that the early branching metazoan Hydra is able to modify bacterial quorum-sensing signals. We identified a eukaryotic mechanism that enables Hydra to spec...
متن کاملEvolutionary theory of bacterial quorum sensing: when is a signal not a signal?
The term quorum sensing (QS) is used to describe the communication between bacterial cells, whereby a coordinated population response is controlled by diffusible molecules produced by individuals. QS has not only been described between cells of the same species (intraspecies), but also between species (interspecies) and between bacteria and higher organisms (inter-kingdom). The fact that QS-bas...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2014
ISSN: 0021-9258
DOI: 10.1074/jbc.m114.573832